Professor Emiel Janssen
Menzies Health Institute Queensland Program Seminar Series
Infectious Diseases & Immunology
Topic: Biobanking - Host: Professor Nigel McMillan
Prof Emiel Janssen - SOLIDTH is a general biobank for all solid and haematological cancers at the Stavanger University Hospital
One information and consent form is being used at different departments, several types of biological material and Patient Reported Outcome Measures (PROM)-data are collected. In this lecture two specific biobanks will be discussed. First, a regional longitudinal prospective breast cancer biobank (PBCB) that will follow ca 1000 patients for 11 years. Biological samples are collected every 6 months and PROM-data annually. The "liquid biopsy kit" comprises various blood sample tubes (Serum, EDTA plasma, EDTA whole blood, PAX-gene and CPT-tubes) and urine. All samples are aliquoted and stored at -80 C. Second, a national prostate cancer biobank which aim is to collect fresh frozen slices from radical prostatectomy according to a standardized method. The samples are collected and stored locally but registered and administered centrally. These examples will illustrate the possibilities and difficulties in establishing biobanks at local, regional and national levels.
Audrey Partanen - Connecting Biobanks: The Victorian Cancer Biobank Model
The value of biobanks and the potential of the high-quality biospecimens stored in their inventories is well recognized by the translational research communities. In 2012, Time featured the "Biobank" as transformative, and "One of the 10 Ideas Changing the World Right Now". Yet collaborative biobanking remains isolated and unconnected which means valuable collections remain static and underutilised. The Victorian Cancer Biobank was established in 2006 and operates as a "virtual biobank" or a "federated model". This means that the collected samples remain at the originating tissue bank sites, but the collections are combined in a virtual sense by transferring all information regarding the tissue sample and access to the collection though a centralized site. This presentation will talk about the evolution of the Victorian Cancer Biobank and some of the bumps and bruises along the way to make the VCB one of the largest biobanking networks in Australia.
Prof Emiel Janssen studied medical biology at the University of Amsterdam. He started his career at the Academic Medical Center in Amsterdam working on neurogenetics. In 2001 he moved to the Department of Pathology at the Stavanger University Hospital. Emiel received his PhD in 2007 at the University in Bergen and is currently the Head of the unit for quantitative and molecular pathology, Head of the laboratory for molecular biology and Head of the research group from the Department of Pathology. Since 2015 Emiel has been Professor in Biomedicine at the University of Stavanger. The group's research is devoted to diminish patient suffering from over- and under-treatment by developing better diagnostics for treatment decision making.
Audrey Partanen is the Executive Officer of the Victorian Cancer Biobank. Audrey moved to Australia from the USA over 15 years ago. She began her career in the USA as a Registered Nurse specialising in surgical oncology before moving into Medical Laboratory Science where she worked and gained considerable experience in clinical and research histopathology departments.
Following her move to Australia, Audrey established the Royal Melbourne Hospital Tissue Bank that has over time, provided the blueprint for the Victorian Cancer Biobank (VCB). She also spent a year at the Wesley Research Institute in Queensland and helped reconfigure the operations of the Wesley's Tissue Bank to more closely align with the VCB model.
Audrey is now in her sixth year as the Executive Officer of the VCB which has evolved into an integrative and collaborative network of research biobanks located in Victoria. She is currently advocating for the establishment of a national biobanking network to help promote standardisation of biobanking practices in Australia.
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